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231223s2009 xx |||||o 00| ||eng c |
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|a 10.1016/j.clim.2009.01.003
|2 doi
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|a pubmed24n0622.xml
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|a (NLM)19217351
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Cuvelier, Geoff D E
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Optimizing outcomes of hematopoietic stem cell transplantation for severe combined immunodeficiency
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|c 2009
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 15.05.2009
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|a Date Revised 13.04.2009
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a This FOCIS Centers of Excellence Short Analytical Review is based on the clinical vignette of two boys from the same family with very different outcomes following hematopoietic stem cell transplantation (HSCT) for X-linked severe combined immunodeficiency (SCID). We review the kinetics of immune reconstitution following HSCT in SCID and emphasize the latest information regarding optimizing transplant outcomes for this disorder. The cases illustrate the difficulties and controversies surrounding the optimal strategies for planning SCID transplants. Specifically, we will focus on 3 areas of current debate and investigation: (i) factors involved in donor selection; (ii) the role of pretransplant conditioning; and (iii) benefits of early HSCT for SCID
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|a Case Reports
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|a Journal Article
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|a Review
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|a IL2RG protein, human
|2 NLM
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|a Interleukin Receptor Common gamma Subunit
|2 NLM
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| 700 |
1 |
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|a Schultz, Kirk R
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Davis, Jeff
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hirschfeld, Aaron F
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Junker, Anne K
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tan, Rusung
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Turvey, Stuart E
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 131(2009), 2 vom: 27. Mai, Seite 179-88
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|x 1521-7035
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|g volume:131
|g year:2009
|g number:2
|g day:27
|g month:05
|g pages:179-88
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|u http://dx.doi.org/10.1016/j.clim.2009.01.003
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