T-bet, pSTAT1 and pSTAT3 expression in peripheral blood mononuclear cells during pregnancy correlates with post-partum activation of multiple sclerosis

In pregnant women affected by multiple sclerosis (MS) we observed increased percentages of CD4(+)CD25(+)Foxp3(+) T regulatory cells at the 1st and the 2nd trimester of gestation that was associated with a decreased T-bet expression in CD4(+) T cells. In women showing clinical relapse and/or new lesi...

Description complète

Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 1 vom: 09. Apr., Seite 70-83
Auteur principal: Iorio, R (Auteur)
Autres auteurs: Frisullo, G, Nociti, V, Patanella, K A, Bianco, A, Marti, A, Mirabella, M, Tonali, P A, Batocchi, A P
Format: Article en ligne
Langue:English
Publié: 2009
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article FOXP3 protein, human Forkhead Transcription Factors Interleukin-17 STAT1 Transcription Factor STAT1 protein, human STAT3 Transcription Factor STAT3 protein, human T-Box Domain Proteins T-bet Transcription Factor plus... Interleukin-10 130068-27-8 Interferon-gamma 82115-62-6