Abnormal neutrophil chemotactic activity in children with congenital insensitivity to pain with anhidrosis (CIPA) : the role of nerve growth factor

A 1926-ins-T mutation in the TrkA gene encoding the tyrosine kinase receptor for nerve growth factor (NGF) was previously documented in patients with congenital insensitivity to pain with anhidrosis (CIPA). These patients suffer from skin lacerations which often evolve into deep tissue infections. A...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 130(2009), 3 vom: 01. März, Seite 365-72
1. Verfasser: Beigelman, Avraham (VerfasserIn)
Weitere Verfasser: Levy, Jacov, Hadad, Nurit, Pinsk, Vered, Haim, Alon, Fruchtman, Yariv, Levy, Rachel
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Chemokines Nerve Growth Factor 9061-61-4 Mitogen-Activated Protein Kinase 3 EC 2.7.11.24 MAP Kinase Kinase 4 EC 2.7.12.2