Abnormal neutrophil chemotactic activity in children with congenital insensitivity to pain with anhidrosis (CIPA) : the role of nerve growth factor

A 1926-ins-T mutation in the TrkA gene encoding the tyrosine kinase receptor for nerve growth factor (NGF) was previously documented in patients with congenital insensitivity to pain with anhidrosis (CIPA). These patients suffer from skin lacerations which often evolve into deep tissue infections. A...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 130(2009), 3 vom: 01. März, Seite 365-72
Auteur principal: Beigelman, Avraham (Auteur)
Autres auteurs: Levy, Jacov, Hadad, Nurit, Pinsk, Vered, Haim, Alon, Fruchtman, Yariv, Levy, Rachel
Format: Article en ligne
Langue:English
Publié: 2009
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Chemokines Nerve Growth Factor 9061-61-4 Mitogen-Activated Protein Kinase 3 EC 2.7.11.24 MAP Kinase Kinase 4 EC 2.7.12.2