Low susceptibility of NC/Nga mice to tumor necrosis factor-alpha-mediated lethality and hepatocellular damage with D-galactosamine sensitization
The susceptibility of NC/Nga mice to tumor necrosis factor (TNF)-alpha was examined by using sensitization with d-galactosamine (d-GalN). Administration of TNF-alpha and d-GalN killed none of the NC/Nga mice, whereas it killed all of the BALB/c mice. Treatment with TNF-alpha and d-GalN caused few he...
Description complète
Détails bibliographiques
Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 130(2009), 2 vom: 11. Feb., Seite 225-32
|
Auteur principal: |
Koide, Naoki
(Auteur) |
Autres auteurs: |
Morikawa, Akiko,
Naiki, Yoshikazu,
Tumurkhuu, Gantsetseg,
Yoshida, Tomoaki,
Ikeda, Hiroshi,
Yokochi, Takashi |
Format: | Article en ligne
|
Langue: | English |
Publié: |
2009
|
Accès à la collection: | Clinical immunology (Orlando, Fla.)
|
Sujets: | Journal Article
Research Support, Non-U.S. Gov't
Antibodies, Monoclonal
Antibodies, Monoclonal, Murine-Derived
Fas protein, mouse
NF-kappa B
Recombinant Proteins
Tumor Necrosis Factor-alpha
anti-Fas monoclonal antibody
fas Receptor
plus...
Galactosamine
7535-00-4
Caspase 3
EC 3.4.22.-
Caspase 8 |