Low susceptibility of NC/Nga mice to tumor necrosis factor-alpha-mediated lethality and hepatocellular damage with D-galactosamine sensitization

The susceptibility of NC/Nga mice to tumor necrosis factor (TNF)-alpha was examined by using sensitization with d-galactosamine (d-GalN). Administration of TNF-alpha and d-GalN killed none of the NC/Nga mice, whereas it killed all of the BALB/c mice. Treatment with TNF-alpha and d-GalN caused few he...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 130(2009), 2 vom: 11. Feb., Seite 225-32
1. Verfasser: Koide, Naoki (VerfasserIn)
Weitere Verfasser: Morikawa, Akiko, Naiki, Yoshikazu, Tumurkhuu, Gantsetseg, Yoshida, Tomoaki, Ikeda, Hiroshi, Yokochi, Takashi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal Antibodies, Monoclonal, Murine-Derived Fas protein, mouse NF-kappa B Recombinant Proteins Tumor Necrosis Factor-alpha anti-Fas monoclonal antibody fas Receptor mehr... Galactosamine 7535-00-4 Caspase 3 EC 3.4.22.- Caspase 8