Low susceptibility of NC/Nga mice to tumor necrosis factor-alpha-mediated lethality and hepatocellular damage with D-galactosamine sensitization

The susceptibility of NC/Nga mice to tumor necrosis factor (TNF)-alpha was examined by using sensitization with d-galactosamine (d-GalN). Administration of TNF-alpha and d-GalN killed none of the NC/Nga mice, whereas it killed all of the BALB/c mice. Treatment with TNF-alpha and d-GalN caused few he...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 130(2009), 2 vom: 11. Feb., Seite 225-32
Auteur principal: Koide, Naoki (Auteur)
Autres auteurs: Morikawa, Akiko, Naiki, Yoshikazu, Tumurkhuu, Gantsetseg, Yoshida, Tomoaki, Ikeda, Hiroshi, Yokochi, Takashi
Format: Article en ligne
Langue:English
Publié: 2009
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal Antibodies, Monoclonal, Murine-Derived Fas protein, mouse NF-kappa B Recombinant Proteins Tumor Necrosis Factor-alpha anti-Fas monoclonal antibody fas Receptor plus... Galactosamine 7535-00-4 Caspase 3 EC 3.4.22.- Caspase 8