Reduced memory B cells in patients with hyper IgE syndrome

Dominant-negative mutations in STAT-3 have recently been found in the majority of patients with sporadic or autosomal-dominant hyper IgE syndrome (HIES). Since STAT-3 plays a role in B cell development and differentiation, we analyzed memory B cells in 20 patients with HIES, 17 of which had STAT-3 m...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 3 vom: 17. Dez., Seite 448-54
1. Verfasser: Speckmann, C (VerfasserIn)
Weitere Verfasser: Enders, A, Woellner, C, Thiel, D, Rensing-Ehl, A, Schlesier, M, Rohr, J, Jakob, T, Oswald, E, Kopp, M V, Sanal, O, Litzman, J, Plebani, A, Pietrogrande, M C, Franco, J L, Espanol, T, Grimbacher, B, Ehl, S
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Multicenter Study Research Support, Non-U.S. Gov't Antibodies, Viral STAT3 Transcription Factor Immunoglobulin E 37341-29-0 DNA 9007-49-2