Dominant-negative mutations in STAT-3 have recently been found in the majority of patients with sporadic or autosomal-dominant hyper IgE syndrome (HIES). Since STAT-3 plays a role in B cell development and differentiation, we analyzed memory B cells in 20 patients with HIES, 17 of which had STAT-3 m...
Bibliographische Detailangaben
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 3 vom: 17. Dez., Seite 448-54
|
1. Verfasser: |
Speckmann, C
(VerfasserIn) |
Weitere Verfasser: |
Enders, A,
Woellner, C,
Thiel, D,
Rensing-Ehl, A,
Schlesier, M,
Rohr, J,
Jakob, T,
Oswald, E,
Kopp, M V,
Sanal, O,
Litzman, J,
Plebani, A,
Pietrogrande, M C,
Franco, J L,
Espanol, T,
Grimbacher, B,
Ehl, S |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2008
|
Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
|
Schlagworte: | Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Antibodies, Viral
STAT3 Transcription Factor
Immunoglobulin E
37341-29-0
DNA
9007-49-2 |