Optimization of functionalized polymer layers for specific targeting of mobile receptors on cell surfaces

The reversible binding between a planar polymer layer functionalized by ligands and a planar cell surface containing different densities of mobile receptors has been studied by Monte Carlo simulations. Using the acceptance-ratio method, the distance-dependent profiles for the average number of ligan...

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Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 24(2008), 22 vom: 18. Nov., Seite 13037-47
Auteur principal: Hagy, Matthew C (Auteur)
Autres auteurs: Wang, Shihu, Dormidontova, Elena E
Format: Article en ligne
Langue:English
Publié: 2008
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, N.I.H., Extramural Ligands Membranes, Artificial Polymers Polyethylene Glycols 3WJQ0SDW1A