Optimization of functionalized polymer layers for specific targeting of mobile receptors on cell surfaces

The reversible binding between a planar polymer layer functionalized by ligands and a planar cell surface containing different densities of mobile receptors has been studied by Monte Carlo simulations. Using the acceptance-ratio method, the distance-dependent profiles for the average number of ligan...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 24(2008), 22 vom: 18. Nov., Seite 13037-47
1. Verfasser: Hagy, Matthew C (VerfasserIn)
Weitere Verfasser: Wang, Shihu, Dormidontova, Elena E
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Ligands Membranes, Artificial Polymers Polyethylene Glycols 3WJQ0SDW1A