The suppressive effect of triptolide on chronic colitis and TNF-alpha/TNFR2 signal pathway in interleukin-10 deficient mice

Recent studies have suggested a critical role of TNFR2 signaling associated with NF-kappaB activation in the pathogenesis of Crohn's disease. Triptolide, an extract from Tripterygium wilfordii Hook, has both anti-immune and anti-inflammatory effects. In this study, we evaluated its possible the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 2 vom: 04. Nov., Seite 211-8
1. Verfasser:	Wei, Xiaowei (VerfasserIn)
Weitere Verfasser:	Gong, Jianfeng, Zhu, Juan, Wang, Pengfei, Li, Ning, Zhu, Weiming, Li, Jieshou
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2008
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Diterpenes Epoxy Compounds Immunosuppressive Agents NF-kappa B Phenanthrenes Receptors, Tumor Necrosis Factor, Type II Tumor Necrosis Factor-alpha Interleukin-10 mehr... 130068-27-8 triptolide 19ALD1S53J