The suppressive effect of triptolide on chronic colitis and TNF-alpha/TNFR2 signal pathway in interleukin-10 deficient mice
Recent studies have suggested a critical role of TNFR2 signaling associated with NF-kappaB activation in the pathogenesis of Crohn's disease. Triptolide, an extract from Tripterygium wilfordii Hook, has both anti-immune and anti-inflammatory effects. In this study, we evaluated its possible the...
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Détails bibliographiques
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 2 vom: 04. Nov., Seite 211-8
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| Auteur principal: |
Wei, Xiaowei
(Auteur) |
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| Autres auteurs: |
Gong, Jianfeng,
Zhu, Juan,
Wang, Pengfei,
Li, Ning,
Zhu, Weiming,
Li, Jieshou |
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| Format: | Article en ligne
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| Langue: | English |
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| Publié: |
2008
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| Accès à la collection: | Clinical immunology (Orlando, Fla.)
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| Sujets: | Journal Article
Research Support, Non-U.S. Gov't
Diterpenes
Epoxy Compounds
Immunosuppressive Agents
NF-kappa B
Phenanthrenes
Receptors, Tumor Necrosis Factor, Type II
Tumor Necrosis Factor-alpha
Interleukin-10
plus...
130068-27-8
triptolide
19ALD1S53J |
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