Photochemical modification and patterning of SU-8 using anthraquinone photolinkers

Bioactive protein patterns and microarrays achieved by selective localization of biomolecules find various applications in biosensors, bio-microelectromechanical systems (bio-MEMS), and in basic protein studies. In this paper we describe simple photochemical methods to fabricate two-dimensional patt...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 24(2008), 18 vom: 16. Sept., Seite 9929-32
1. Verfasser: Blagoi, Gabriela (VerfasserIn)
Weitere Verfasser: Keller, Stephan, Persson, Fredrik, Boisen, Anja, Jakobsen, Mogens Havsteen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Anthraquinones Coloring Agents Cross-Linking Reagents Epoxy Compounds Polymers Proteins SU-8 compound
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520 |a Bioactive protein patterns and microarrays achieved by selective localization of biomolecules find various applications in biosensors, bio-microelectromechanical systems (bio-MEMS), and in basic protein studies. In this paper we describe simple photochemical methods to fabricate two-dimensional patterns on a Novolac A derivative polymer (SU-8) and, subsequently, their functionalization with biomolecules. Anthraquinone (AQ) derivatives are used to chemically modify and pattern SU-8 surfaces. Features as small as 20 mum are obtained when using uncollimated light. The X-Y spatial resolution of micropatterned AQ molecules is improved to 1.5 mum when a collimated light source is used. This micropatterning process will be important for the functionalization of MEMS-based biosensors. The method saves several processing steps and can be integrated in cleanroom fabrication thus avoiding contamination of the sensor surfaces 
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650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a Coloring Agents  |2 NLM 
650 7 |a Cross-Linking Reagents  |2 NLM 
650 7 |a Epoxy Compounds  |2 NLM 
650 7 |a Polymers  |2 NLM 
650 7 |a Proteins  |2 NLM 
650 7 |a SU-8 compound  |2 NLM 
700 1 |a Keller, Stephan  |e verfasserin  |4 aut 
700 1 |a Persson, Fredrik  |e verfasserin  |4 aut 
700 1 |a Boisen, Anja  |e verfasserin  |4 aut 
700 1 |a Jakobsen, Mogens Havsteen  |e verfasserin  |4 aut 
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