In vitro expanded human invariant natural killer T-cells promote functional activity of natural killer cells

Invariant natural killer T (iNKT) cells play a pivotal role in cancer immunity through trans-activation of effector cells via swift cytokine secretion. In mice, iNKT cell activation by alpha-galactosylceramide (alpha-GC) induces potent NK cell-mediated anti-tumour effects. Here we investigated wheth...

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Publié dans:	Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 1 vom: 08. Okt., Seite 145-54
Auteur principal:	Moreno, María (Auteur)
Autres auteurs:	Molling, Johan W, von Mensdorff-Pouilly, Silvia, Verheijen, René H M, von Blomberg, B Mary E, van den Eertwegh, Alfons J M, Scheper, Rik J, Bontkes, Hetty J
Format:	Article en ligne
Langue:	English
Publié:	2008
Accès à la collection:	Clinical immunology (Orlando, Fla.)
Sujets:	Journal Article Galactosylceramides Interleukins alpha-galactosylceramide Interferon-gamma 82115-62-6 Interleukin-21 MKM3CA6LT1