OBJECTIVE: Chemokine receptors are G-protein coupled receptors (GPCRs) phosphorylated by G-protein receptor kinases (GRKs) after ligand-mediated activation. We hypothesized that GRK subtypes differentially regulate granulocyte chemotaxis and clinical disease expression in the K/BxN model
Détails bibliographiques
Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 1 vom: 15. Okt., Seite 115-22
|
Auteur principal: |
Tarrant, Teresa K
(Auteur) |
Autres auteurs: |
Rampersad, Rishi R,
Esserman, Denise,
Rothlein, Lisa R,
Liu, Peng,
Premont, Richard T,
Lefkowitz, Robert J,
Lee, David M,
Patel, Dhavalkumar D |
Format: | Article en ligne
|
Langue: | English |
Publié: |
2008
|
Accès à la collection: | Clinical immunology (Orlando, Fla.)
|
Sujets: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Interleukin-6
Leukotriene B4
1HGW4DR56D
Complement C5a
80295-54-1
GRK2 protein, mouse
EC 2.7.11.15
plus...
G-Protein-Coupled Receptor Kinase 2
EC 2.7.11.16
G-Protein-Coupled Receptor Kinases
G-protein-coupled receptor kinase 6 |