Identification of CTLA-4 isoforms produced by alternative splicing and their association with myasthenia gravis

Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness induced by autoantibodies against the acetylcholine receptor. CTLA-4 (CD152) plays an inhibitory role in the immune response and has been suggested to be involved in the pathophysiology of MG. In this study, we focused...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 3 vom: 15. Sept., Seite 374-81
1. Verfasser: Gu, Ming (VerfasserIn)
Weitere Verfasser: Kakoulidou, Maria, Giscombe, Ricardo, Pirskanen, Ritva, Lefvert, Ann Kari, Klareskog, Lars, Wang, XiongBiao
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, CD CTLA-4 Antigen CTLA4 protein, human Protein Isoforms RNA, Messenger