CC-4047 promotes Th1 cell differentiation and reprograms polarized human Th2 cells by enhancing transcription factor T-bet
The IMiDs immunomodulatory drugs are an expanding family of compounds under investigation in a broad range of diseases because they exhibit immunomodulatory and anti-tumorigenic properties. Although the molecular targets remain unidentified, the broad activity of select IMiDs immunomodulatory drugs...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 3 vom: 15. Sept., Seite 392-9
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| 1. Verfasser: |
Xu, Weiming
(VerfasserIn) |
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| Weitere Verfasser: |
Celeridad, Maria,
Sankar, Sabita,
Webb, David R,
Bennett, Brydon L |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2008
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
GATA3 Transcription Factor
GATA3 protein, human
Interleukin-2
Receptors, Antigen, T-Cell
T-Box Domain Proteins
T-box transcription factor TBX21
Tumor Necrosis Factor-alpha
Thalidomide
4Z8R6ORS6L
mehr...
Interferon-gamma
82115-62-6
pomalidomide
D2UX06XLB5 |
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