Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis

Expansion of circulating CD28- T-cells reminiscent of effector memory T-cells (T(EM)) has been reported in Wegener's granulomatosis (WG) recently. To investigate the role of T(EM) in WG, we analyzed the expression of the activating NK-receptor NKG2D and its ligand MIC on circulating T(EM) and i...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 2 vom: 15. Mai, Seite 144-50
1. Verfasser: Capraru, Dorin (VerfasserIn)
Weitere Verfasser: Müller, Antje, Csernok, Elena, Gross, Wolfgang L, Holl-Ulrich, Konstanze, Northfield, John, Klenerman, Paul, Herlyn, Karen, Holle, Julia, Gottschlich, Stefan, Voswinkel, Jan, Spies, Thomas, Fagin, Ursula, Jabs, Wolfram J, Lamprecht, Peter
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't CD28 Antigens GPI-Linked Proteins Intercellular Signaling Peptides and Proteins Interleukin-15 KLRK1 protein, human NK Cell Lectin-Like Receptor Subfamily K Receptors, Immunologic Receptors, Natural Killer Cell mehr... ULBP2 protein, human Myeloblastin EC 3.4.21.76