Unambiguous structural elucidation of base-modified purine nucleosides using NMR

Copyright (c) 2007 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 46(2008), 1 vom: 01. Jan., Seite 1-8
1. Verfasser: Narukulla, Raman (VerfasserIn)
Weitere Verfasser: Shuker, David E G, Ramesh, Vasudevan, Xu, Yao-Zhong
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Carbohydrates Protons Purine Nucleosides Purine Nucleotides
LEADER 01000naa a22002652 4500
001 NLM175379467
003 DE-627
005 20231223141905.0
007 cr uuu---uuuuu
008 231223s2008 xx |||||o 00| ||eng c
028 5 2 |a pubmed24n0585.xml 
035 |a (DE-627)NLM175379467 
035 |a (NLM)18041011 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Narukulla, Raman  |e verfasserin  |4 aut 
245 1 0 |a Unambiguous structural elucidation of base-modified purine nucleosides using NMR 
264 1 |c 2008 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 25.04.2008 
500 |a Date Revised 20.10.2021 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Copyright (c) 2007 John Wiley & Sons, Ltd. 
520 |a A general and unambiguous approach has been developed for structural elucidation of modified purine nucleosides using NMR spectroscopy. Systematic assignment of proton and carbon signals of modified nucleosides was firmly established by COSY and the anomerism of the glycosidic linkage of synthetic nucleosides clearly elucidated by NOESY experiments. Characteristic properties of 15N-isotopic labelling at specific positions of nucleosides were also employed for structural studies. The reported approach is applicable to other modified nucleosides and nucleotides, as well as nucleobases 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Carbohydrates  |2 NLM 
650 7 |a Protons  |2 NLM 
650 7 |a Purine Nucleosides  |2 NLM 
650 7 |a Purine Nucleotides  |2 NLM 
700 1 |a Shuker, David E G  |e verfasserin  |4 aut 
700 1 |a Ramesh, Vasudevan  |e verfasserin  |4 aut 
700 1 |a Xu, Yao-Zhong  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Magnetic resonance in chemistry : MRC  |d 1985  |g 46(2008), 1 vom: 01. Jan., Seite 1-8  |w (DE-627)NLM098179667  |x 1097-458X  |7 nnns 
773 1 8 |g volume:46  |g year:2008  |g number:1  |g day:01  |g month:01  |g pages:1-8 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 46  |j 2008  |e 1  |b 01  |c 01  |h 1-8