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|a eng
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|a Narukulla, Raman
|e verfasserin
|4 aut
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|a Unambiguous structural elucidation of base-modified purine nucleosides using NMR
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|c 2008
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|a Text
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 25.04.2008
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|a Date Revised 20.10.2021
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright (c) 2007 John Wiley & Sons, Ltd.
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|a A general and unambiguous approach has been developed for structural elucidation of modified purine nucleosides using NMR spectroscopy. Systematic assignment of proton and carbon signals of modified nucleosides was firmly established by COSY and the anomerism of the glycosidic linkage of synthetic nucleosides clearly elucidated by NOESY experiments. Characteristic properties of 15N-isotopic labelling at specific positions of nucleosides were also employed for structural studies. The reported approach is applicable to other modified nucleosides and nucleotides, as well as nucleobases
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Carbohydrates
|2 NLM
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|a Protons
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|a Purine Nucleosides
|2 NLM
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|a Purine Nucleotides
|2 NLM
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|a Shuker, David E G
|e verfasserin
|4 aut
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|a Ramesh, Vasudevan
|e verfasserin
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|a Xu, Yao-Zhong
|e verfasserin
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|t Magnetic resonance in chemistry : MRC
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|g 46(2008), 1 vom: 01. Jan., Seite 1-8
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