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231223s2007 xx ||||| 00| ||eng c |
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|a (NLM)17676778
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Liu, Chuanjun
|e verfasserin
|4 aut
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| 245 |
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|a Intercalation interactions between dsDNA and acridine studied by single molecule force spectroscopy
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|c 2007
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 02.10.2007
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|a Date Revised 21.08.2007
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a In this letter, we report on the direct measurement of the intercalation interactions between acridine and double-stranded DNA (dsDNA) using single molecule force spectroscopy. The interaction between acridine and dsDNA is broken by force of 36 pN at a loading rate of 5.0 nN/s. The most probable rupture force between acridine and dsDNA is dependent on the loading rate, indicating that the binding of acridine and dsDNA is a dynamic process. The combination of SMFS experimental data with the theoretical model clearly suggests the presence of two energy barriers along with an unbinding trajectory of acridine-dsDNA
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Acridines
|2 NLM
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|a Intercalating Agents
|2 NLM
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|a DNA
|2 NLM
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|a 9007-49-2
|2 NLM
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| 700 |
1 |
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|a Jiang, Zhenhua
|e verfasserin
|4 aut
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| 700 |
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|a Zhang, Yiheng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Zhiqiang
|e verfasserin
|4 aut
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| 700 |
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|a Zhang, Xi
|e verfasserin
|4 aut
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| 700 |
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|a Feng, Fude
|e verfasserin
|4 aut
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| 700 |
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|a Wang, Shu
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1999
|g 23(2007), 18 vom: 28. Aug., Seite 9140-2
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:23
|g year:2007
|g number:18
|g day:28
|g month:08
|g pages:9140-2
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