Syk kinase as a treatment target for therapy in autoimmune diseases
Spleen tyrosine kinase (Syk) associates with a variety of immunoreceptors in myeloid and lymphoid cells. Syk initiates intracellular signaling once the receptor is engaged by its ligand. Blocking Syk may prove beneficial in interrupting the propagation of the abnormal immune response in both autoimm...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 3 vom: 01. Sept., Seite 235-7 |
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| Format: | Aufsatz |
| Sprache: | English |
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2007
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Comment Intracellular Signaling Peptides and Proteins Ligands Protein Kinase Inhibitors Receptors, IgG Protein-Tyrosine Kinases EC 2.7.10.1 SYK protein, human EC 2.7.10.2 |