Sensitivity enhancement in saturation transfer difference (STD) experiments through optimized excitation schemes

Sensitivity enhancement in saturation transfer difference (STD) experiments through optimized excitation schemes

Investigation of ligand-protein interactions by the saturation transfer difference (STD) experiment has been well established in the drug discovery process through numerous examples. Thus, binding epitopes may be mapped by comparing signals of the ligand with and without saturation of the protein. H...

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Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 45(2007), 9 vom: 06. Sept., Seite 720-4
1. Verfasser: Cutting, Brian (VerfasserIn)
Weitere Verfasser: Shelke, Sachin V, Dragic, Zorica, Wagner, Beatrice, Gathje, Heiko, Kelm, Soerge, Ernst, Beat
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't E-Selectin Epitopes Glycoproteins Ligands Myelin-Associated Glycoprotein Serum Albumin