Maximizing CD8+ T cell responses elicited by peptide vaccines containing CpG oligodeoxynucleotides

We assessed the ability of several factors to increase the size of tumor-antigen-specific CD8(+) T cell responses elicited by vaccines incorporating peptides and CpG-containing oligodeoxynucleotides (CpG). Neither granulocyte-macrophage colony-stimulating factor (GM-CSF) nor an immunogenic MHC class...

Description complète

Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 2 vom: 20. Aug., Seite 119-30
Auteur principal: Kochenderfer, James N (Auteur)
Autres auteurs: Chien, Christopher D, Simpson, Jessica L, Gress, Ronald E
Format: Article
Langue:English
Publié: 2007
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, N.I.H., Intramural Adjuvants, Immunologic CPG-oligonucleotide Cancer Vaccines Epitopes Interleukin-2 Oligodeoxyribonucleotides Peptide Fragments Vaccines, Subunit plus... Granulocyte-Macrophage Colony-Stimulating Factor 83869-56-1 Intramolecular Oxidoreductases EC 5.3.- dopachrome isomerase EC 5.3.3.12