Maximizing CD8+ T cell responses elicited by peptide vaccines containing CpG oligodeoxynucleotides

Maximizing CD8+ T cell responses elicited by peptide vaccines containing CpG oligodeoxynucleotides

We assessed the ability of several factors to increase the size of tumor-antigen-specific CD8(+) T cell responses elicited by vaccines incorporating peptides and CpG-containing oligodeoxynucleotides (CpG). Neither granulocyte-macrophage colony-stimulating factor (GM-CSF) nor an immunogenic MHC class...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 2 vom: 20. Aug., Seite 119-30
1. Verfasser: Kochenderfer, James N (VerfasserIn)
Weitere Verfasser: Chien, Christopher D, Simpson, Jessica L, Gress, Ronald E
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Intramural Adjuvants, Immunologic CPG-oligonucleotide Cancer Vaccines Epitopes Interleukin-2 Oligodeoxyribonucleotides Peptide Fragments Vaccines, Subunit mehr... Granulocyte-Macrophage Colony-Stimulating Factor 83869-56-1 Intramolecular Oxidoreductases EC 5.3.- dopachrome isomerase EC 5.3.3.12