Immunogenicity of singlet oxygen modified human DNA : implications for anti-DNA antibodies in systemic lupus erythematosus
Reactive oxygen species (ROS)-modified DNA has been shown to be a better and more discriminating immunogen than native DNA (nDNA) for the production of anti-DNA autoantibodies in SLE (systemic lupus erythematosus). Among ROS, the role of hydroxyl radical (.OH) in the induction of damage and modifica...
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 1 vom: 28. Juli, Seite 83-9 |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article |
| Langue: | English |
| Publié: |
2007
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| Accès à la collection: | Clinical immunology (Orlando, Fla.) |
| Sujets: | Journal Article Antibodies, Antinuclear Immune Sera Singlet Oxygen 17778-80-2 DNA 9007-49-2 Methylene Blue T42P99266K |