Immunogenicity of singlet oxygen modified human DNA implications for anti-DNA antibodies in systemic lupus erythematosus

Immunogenicity of singlet oxygen modified human DNA : implications for anti-DNA antibodies in systemic lupus erythematosus

Reactive oxygen species (ROS)-modified DNA has been shown to be a better and more discriminating immunogen than native DNA (nDNA) for the production of anti-DNA autoantibodies in SLE (systemic lupus erythematosus). Among ROS, the role of hydroxyl radical (.OH) in the induction of damage and modifica...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 1 vom: 28. Juli, Seite 83-9
1. Verfasser: Al Arfaj, Abdurahman Saud (VerfasserIn)
Weitere Verfasser: Chowdhary, Abdul Rauf, Khalil, Najma, Ali, Rashid
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Antibodies, Antinuclear Immune Sera Singlet Oxygen 17778-80-2 DNA 9007-49-2 Methylene Blue T42P99266K