Presentation of HCV antigens to naive CD8+T cells : why the where, when, what and how are important for virus control and infection outcome

T cell-mediated protection against HCV depends on constantly activated effector CD8(+)T cells that control emergence, spread and expansion of the virus. Why these cells fail to contain HCV replication in 70-80% of the individuals who develop persistent viremia is not clear. Although many reviews hav...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 1 vom: 28. Juli, Seite 5-12
Auteur principal: Racanelli, Vito (Auteur)
Autres auteurs: Manigold, Tobias
Format: Article
Langue:English
Publié: 2007
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Review Hepatitis C Antibodies Hepatitis C Antigens