Presentation of HCV antigens to naive CD8+T cells : why the where, when, what and how are important for virus control and infection outcome

T cell-mediated protection against HCV depends on constantly activated effector CD8(+)T cells that control emergence, spread and expansion of the virus. Why these cells fail to contain HCV replication in 70-80% of the individuals who develop persistent viremia is not clear. Although many reviews hav...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 124(2007), 1 vom: 28. Juli, Seite 5-12
1. Verfasser: Racanelli, Vito (VerfasserIn)
Weitere Verfasser: Manigold, Tobias
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Review Hepatitis C Antibodies Hepatitis C Antigens