Site specificity of alpha-H abstraction reaction among secondary structure motif--an ab initio study

The initial step of protein oxidation is studied through alpha-H abstraction by an OH radical with various secondary structure motifs of proteins. It is found that there exist preferential alpha-Hs in this kind of abstractions. The typical abstraction mechanism involves three steps: forming a pre-re...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of computational chemistry. - 1984. - 28(2007), 4 vom: 01. März, Seite 783-94
1. Verfasser: Lu, Hsiu-Feng (VerfasserIn)
Weitere Verfasser: Li, Feng-Yin, Lin, S H
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Journal of computational chemistry
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Peptides Proteins Hydrogen 7YNJ3PO35Z