Thiol-mediated anchoring of ligands to self-assembled monolayers for studies of biospecific interactions

We report a method to immobilize thiol-containing ligands onto self-assembled monolayers (SAMs) of alkanethiolates presenting chloracetylated hexa(ethylene glycol) groups. The chloroacetyl groups react with thiols under mild basic conditions, enabling the stable immobilization of biologically active...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 22(2006), 24 vom: 21. Nov., Seite 10157-62
1. Verfasser: Gujraty, Kunal V (VerfasserIn)
Weitere Verfasser: Ashton, Randolph, Bethi, Sridhar R, Kate, Sandesh, Faulkner, Christopher J, Jennings, G Kane, Kane, Ravi S
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Alkanes Ligands Oligopeptides Proteins Sulfhydryl Compounds Sulfonamides neutravidin Avidin 1405-69-2 mehr... Biotin 6SO6U10H04 arginyl-glycyl-aspartic acid 78VO7F77PN Carbonic Anhydrases EC 4.2.1.1 Benzene J64922108F