Inhibition of oxidation activity of myeloperoxidase (MPO) by propylthiouracil (PTU) and anti-MPO antibodies from patients with PTU-induced vasculitis
Propylthiouracil (PTU) could induce antineutrophil cytoplasmic antibody (ANCA) associated vasculitis. This study aimed to investigate the inhibitory effects on MPO oxidation activity by PTU and MPO-ANCA from patients with primary microscopic polyangiitis (MPA) and PTU-induced vasculitis. IgG prepara...
Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 122(2007), 2 vom: 01. Feb., Seite 187-93 |
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Auteur principal: | |
Autres auteurs: | , , , |
Format: | Article |
Langue: | English |
Publié: |
2007
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Accès à la collection: | Clinical immunology (Orlando, Fla.) |
Sujets: | Journal Article Research Support, Non-U.S. Gov't Antibodies, Antineutrophil Cytoplasmic Antimetabolites Propylthiouracil 721M9407IY Peroxidase EC 1.11.1.7 Myeloblastin EC 3.4.21.76 |