Inhibition of oxidation activity of myeloperoxidase (MPO) by propylthiouracil (PTU) and anti-MPO antibodies from patients with PTU-induced vasculitis

Inhibition of oxidation activity of myeloperoxidase (MPO) by propylthiouracil (PTU) and anti-MPO antibodies from patients with PTU-induced vasculitis

Propylthiouracil (PTU) could induce antineutrophil cytoplasmic antibody (ANCA) associated vasculitis. This study aimed to investigate the inhibitory effects on MPO oxidation activity by PTU and MPO-ANCA from patients with primary microscopic polyangiitis (MPA) and PTU-induced vasculitis. IgG prepara...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 122(2007), 2 vom: 01. Feb., Seite 187-93
1. Verfasser: Zhang, Ai-Hua (VerfasserIn)
Weitere Verfasser: Chen, Min, Gao, Ying, Zhao, Ming-Hui, Wang, Hai-Yan
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibodies, Antineutrophil Cytoplasmic Antimetabolites Propylthiouracil 721M9407IY Peroxidase EC 1.11.1.7 Myeloblastin EC 3.4.21.76