Defect internalization and tyrosine kinase activation in Aire deficient antigen presenting cells exposed to Candida albicans antigens
Patients with Autoimmune polyendocrine syndrome type I (APS I) present with multiple endocrine failures due to organ-specific autoimmune disease, thought to be T-cell-mediated. Paradoxically, APS I patients suffer from chronic mucocutaneous candidiasis. The mutated gene has been identified as the Au...
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 3 vom: 15. Dez., Seite 265-73 |
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| Auteur principal: | |
| Autres auteurs: | , , , |
| Format: | Article |
| Langue: | English |
| Publié: |
2006
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| Accès à la collection: | Clinical immunology (Orlando, Fla.) |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Antigens, Fungal Cell Extracts Fungal Proteins Transcription Factors Zymosan 9010-72-4 Protein-Tyrosine Kinases EC 2.7.10.1 |