Defect internalization and tyrosine kinase activation in Aire deficient antigen presenting cells exposed to Candida albicans antigens

Patients with Autoimmune polyendocrine syndrome type I (APS I) present with multiple endocrine failures due to organ-specific autoimmune disease, thought to be T-cell-mediated. Paradoxically, APS I patients suffer from chronic mucocutaneous candidiasis. The mutated gene has been identified as the Au...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 3 vom: 25. Dez., Seite 265-73
1. Verfasser: Brännström, Johan (VerfasserIn)
Weitere Verfasser: Hässler, Signe, Peltonen, Leena, Herrmann, Björn, Winqvist, Ola
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, Fungal Cell Extracts Fungal Proteins Transcription Factors Zymosan 9010-72-4 Protein-Tyrosine Kinases EC 2.7.10.1