Defect internalization and tyrosine kinase activation in Aire deficient antigen presenting cells exposed to Candida albicans antigens

Defect internalization and tyrosine kinase activation in Aire deficient antigen presenting cells exposed to Candida albicans antigens

Patients with Autoimmune polyendocrine syndrome type I (APS I) present with multiple endocrine failures due to organ-specific autoimmune disease, thought to be T-cell-mediated. Paradoxically, APS I patients suffer from chronic mucocutaneous candidiasis. The mutated gene has been identified as the Au...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 121(2006), 3 vom: 25. Dez., Seite 265-73
1. Verfasser: Brännström, Johan (VerfasserIn)
Weitere Verfasser: Hässler, Signe, Peltonen, Leena, Herrmann, Björn, Winqvist, Ola
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, Fungal Cell Extracts Fungal Proteins Transcription Factors Zymosan 9010-72-4 Protein-Tyrosine Kinases EC 2.7.10.1