DNA condensation and interaction with zwitterionic phospholipids mediated by divalent cations

Artificial viruses are considered to be a promising tool in gene therapy. To find lipid-DNA complexes with high transfection efficiency but without toxicity is a fundamental aim. Although cationic lipids are frequently toxic for cells, neutral lipids are completely nontoxic. Zwitterionic lipids do n...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 22(2006), 14 vom: 04. Juli, Seite 6293-301
1. Verfasser: Gromelski, Sandra (VerfasserIn)
Weitere Verfasser: Brezesinski, Gerald
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Cations, Divalent Membranes, Artificial Phosphatidylethanolamines DNA 9007-49-2 calf thymus DNA 91080-16-9 Calcium mehr... SY7Q814VUP 1,2-dimyristoylphosphatidylethanolamine Z37OX1ASNK