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DE-627 |
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231223s2006 xx ||||| 00| ||chi c |
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|a pubmed25n0545.xml
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|a (DE-627)NLM163567697
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|a (NLM)16780715
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Xie, Zheng-de
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Genotype of wild-type measles viruses circulating in Beijing in 2003
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1 |
|c 2006
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 20.07.2010
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| 500 |
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|a Date Revised 09.12.2020
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a OBJECTIVE: To investigate genotype of wild-type measles viruses circulated in Beijing in 2003
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|a METHODS: Throat swabs specimens were collected from patients seen during an outbreak of measles and from clinically suspected sporadic measles patients in 2003. Vero/SLAM cell lines recommended by WHO were used to isolate measles virus. Four hundreds and fifty nucleotides of COOH-terminal of nucleoprotein (N) genes were amplified by using PR-PCR. The amplified products were sequenced and the sequences were compared with references viruses from GeneBank
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|a RESULTS: Eight strains of measles viruses were isolated from throat swabs of patients who came from seven districts and counties of Beijing. Sequence analysis of the 450 nucleotides of COOH-terminal of nucleoprotein (N) genes indicated that these 8 strains belonged to H1a genotype. The average genetic distances of these 8 strains to H1a genotype, Chin9322, H1b genotype, Chin9475 and H1c genotype, Chin9427, were 0.004 - 0.011, 0.026 - 0.031 and 0.015 - 0.022, respectively. The average genetic distances of these 8 strains to H1a genotype, Anhui 01 - 1/Anhui 02 - 2, were 0.000 - 0.009 (0 - 5 nucleotide variation)
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|a CONCLUSIONS: Major genotypes of wild-type measles viruses circulated in Beijing in 2003 were H1a genotype. The genotypes H1c, H1b and H2 may have disappeared in Beijing
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|a Journal Article
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|a Immunoglobulin M
|2 NLM
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|a Nucleocapsid Proteins
|2 NLM
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| 650 |
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7 |
|a Nucleoproteins
|2 NLM
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| 650 |
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|a RNA, Viral
|2 NLM
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| 650 |
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7 |
|a Viral Proteins
|2 NLM
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| 650 |
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|a nucleoprotein, Measles virus
|2 NLM
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| 700 |
1 |
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|a Ji, Yi-xin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Ya-yi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Hui
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Chun-yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yan, Jing
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Mai, Ying
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Shen, Kun-ling
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Xu, Wen-bo
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 44(2006), 5 vom: 19. Mai, Seite 364-8
|w (DE-627)NLM136249191
|x 0578-1310
|7 nnns
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| 773 |
1 |
8 |
|g volume:44
|g year:2006
|g number:5
|g day:19
|g month:05
|g pages:364-8
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|a GBV_USEFLAG_A
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|a SYSFLAG_A
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|a AR
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|d 44
|j 2006
|e 5
|b 19
|c 05
|h 364-8
|