Autoimmunity during lymphopenia : a two-hit model

The immune system has evolved elaborate mechanisms to respond to diverse antigens while minimizing the risk for autoimmune reactivity. During lymphopenia, however, some mechanisms that normally serve to maintain host tolerance are temporarily suspended. Peripheral T cells proliferate in response to...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 2 vom: 05. Aug., Seite 121-8
Auteur principal: Krupica, Tom Jr (Auteur)
Autres auteurs: Fry, Terry J, Mackall, Crystal L
Format: Article
Langue:English
Publié: 2006
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't Review Interleukins Interleukin-21 MKM3CA6LT1