Autoimmunity during lymphopenia a two-hit model

Autoimmunity during lymphopenia : a two-hit model

The immune system has evolved elaborate mechanisms to respond to diverse antigens while minimizing the risk for autoimmune reactivity. During lymphopenia, however, some mechanisms that normally serve to maintain host tolerance are temporarily suspended. Peripheral T cells proliferate in response to...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 2 vom: 05. Aug., Seite 121-8
1. Verfasser: Krupica, Tom Jr (VerfasserIn)
Weitere Verfasser: Fry, Terry J, Mackall, Crystal L
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't Review Interleukins Interleukin-21 MKM3CA6LT1