Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors

Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors

Glucocorticoids (GCs) are widely used as anti-inflammatory and immunosuppressive agents. Effects of GC have mainly been attributed to the suppression of T cells. Recently, several studies have indicated the role of dendritic cells (DC) in GC-mediated immunosuppression. We investigated the effect of...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 3 vom: 15. Sept., Seite 260-71
1. Verfasser: Rozkova, Daniela (VerfasserIn)
Weitere Verfasser: Horvath, Rudolf, Bartunkova, Jirina, Spisek, Radek
Format: Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Cytokines Glucocorticoids Toll-Like Receptors Dexamethasone 7S5I7G3JQL Prednisone VB0R961HZT Methylprednisolone X4W7ZR7023