TCR vaccination in aluminum adjuvant protects against autoimmune encephalomyelitis
Experimental Allergic Encephalomyelitis (EAE) is a neuroinflammatory, autoimmune disorder in which myelin-reactive Th1 T cells with a restricted TCRVbeta repertoire play a pathogenic role. Here, I show that an engineered single-chain TCR containing dominant TCRValpha/Vbeta encephalitogenic elements,...
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 3 vom: 18. Juni, Seite 252-60 |
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| Auteur principal: | |
| Format: | Article |
| Langue: | English |
| Publié: |
2006
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| Accès à la collection: | Clinical immunology (Orlando, Fla.) |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Adjuvants, Immunologic Antibodies Cytokines Glycoproteins Myelin-Oligodendrocyte Glycoprotein Peptide Fragments Receptors, Antigen, T-Cell Recombinant Proteins plus... |