TCR vaccination in aluminum adjuvant protects against autoimmune encephalomyelitis
Experimental Allergic Encephalomyelitis (EAE) is a neuroinflammatory, autoimmune disorder in which myelin-reactive Th1 T cells with a restricted TCRVbeta repertoire play a pathogenic role. Here, I show that an engineered single-chain TCR containing dominant TCRValpha/Vbeta encephalitogenic elements,...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 119(2006), 3 vom: 18. Juni, Seite 252-60 |
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| Format: | Aufsatz |
| Sprache: | English |
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2006
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Adjuvants, Immunologic Antibodies Cytokines Glycoproteins Myelin-Oligodendrocyte Glycoprotein Peptide Fragments Receptors, Antigen, T-Cell Recombinant Proteins mehr... |