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231223s2004 xx ||||| 00| ||eng c |
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|a (NLM)15969172
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|a DE-627
|b ger
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|e rakwb
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|a eng
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1 |
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|a Richter, Ralf P
|e verfasserin
|4 aut
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|a QCM-D on mica for parallel QCM-D-AFM studies
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|c 2004
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Date Completed 12.01.2006
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|a Date Revised 26.10.2019
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|a published: Print
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|a Citation Status MEDLINE
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|a Quartz crystal microbalance with dissipation monitoring (QCM-D) has developed into a recognized method to study adsorption processes in liquid, such as the formation of supported lipid bilayers and protein adsorption. However, the large intrinsic roughness of currently used gold-coated or silica-coated QCM-D sensors limits parallel structural characterization by atomic force microscopy (AFM). We present a method for coating QCM-D sensors with thin mica sheets operating in liquid with high stability and sensitivity. We define criteria to objectively assess the reliability of the QCM-D measurements and demonstrate that the mica-coated sensors can be used to follow the formation of supported lipid membranes and subsequent protein adsorption. This method allows combining QCM-D and AFM investigations on identical supports, providing detailed physicochemical and structural characterization of model membranes
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|a Journal Article
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|a Aluminum Silicates
|2 NLM
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|a Annexin A5
|2 NLM
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|a Lipid Bilayers
|2 NLM
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|a Phosphatidylcholines
|2 NLM
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|a Phosphatidylserines
|2 NLM
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|a Water
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|a 059QF0KO0R
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|a Quartz
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|a 1,2-dioleoylphosphatidylserine
|2 NLM
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|a 70614-14-1
|2 NLM
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|a 1,2-oleoylphosphatidylcholine
|2 NLM
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|a EDS2L3ODLV
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|a mica
|2 NLM
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|a V8A1AW0880
|2 NLM
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1 |
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|a Brisson, Alain
|e verfasserin
|4 aut
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773 |
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8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 20(2004), 11 vom: 25. Mai, Seite 4609-13
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnas
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773 |
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|g volume:20
|g year:2004
|g number:11
|g day:25
|g month:05
|g pages:4609-13
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