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01000caa a22002652 4500 |
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NLM155225618 |
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DE-627 |
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20250206092954.0 |
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tu |
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231223s2005 xx ||||| 00| ||chi c |
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|a pubmed25n0518.xml
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|a (DE-627)NLM155225618
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|a (NLM)15877961
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Chen, Xiao-dong
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Effect of aloe vera polysaccharide on the release of cytokines and nitric oxide in cultured human keratinocytes
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| 264 |
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1 |
|c 2005
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 11.12.2009
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE: To investigate the effects of polysaccharide extracted from Aloe Barbadensis on the release of cytokines and nitric oxide (NO) in cultured human keratinocytes
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|a METHODS: The levels of transforming growth factor-alpha (TGF-alpha), TGF-beta1, interleukin-1beta (IL-1beta), IL-6, IL-8, tumor necrosis factor (TNF) and NO in the supernatants of keratinocyte culture in which culture media containing 25, 50, 100, 200, 400 microg/ml, respectively of aloe polysaccharide were assayed. In the control group equal volume of media without the polysaccharide was used
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| 520 |
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|a RESULTS: Compared with control group, the levels of TGF-alpha, TGF-beta1, IL-1beta, IL-6, IL-8 and TNF in the supernatants of cultured keratinocytes were significantly higher when aloe polysaccharide was added (P<0.05 or P<0.01), and they were positively correlated to the concentration of aloe polysaccharide (P<0.01). However, aloe polysaccharide markedly decreased the level of NO in a dose dependent manner (P<0.01)
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|a CONCLUSION: Aloe polysaccharide could promote keratinocytes to secrete TGF-alpha, TGF-beta1, IL-1beta, IL-6, IL-8 and TNF, and inhibit the release of NO
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|a English Abstract
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Cytokines
|2 NLM
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| 650 |
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|a Polysaccharides
|2 NLM
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| 650 |
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|a Nitric Oxide
|2 NLM
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| 650 |
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7 |
|a 31C4KY9ESH
|2 NLM
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| 700 |
1 |
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|a Huang, Li-ying
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wu, Bo-yu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Jiang, Qiong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Zhong-cheng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lin, Xin-hua
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 17(2005), 5 vom: 09. Mai, Seite 296-8
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
1 |
8 |
|g volume:17
|g year:2005
|g number:5
|g day:09
|g month:05
|g pages:296-8
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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|a GBV_ILN_350
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| 951 |
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|a AR
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| 952 |
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|d 17
|j 2005
|e 5
|b 09
|c 05
|h 296-8
|