Regiospecific control of protein expression in cells cultured on two-component counter gradients of extracellular matrix proteins

Regiospecific control of protein expression in cells cultured on two-component counter gradients of extracellular matrix proteins

This work describes the use of microfluidic tools to generate covalently immobilized counter gradients of extracellular matrix (ECM) proteins laminin and collagen I. Using these platforms, we demonstrate control of the expression levels of two proteins linked to cell cycle progression by virtue of t...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 21(2005), 7 vom: 29. März, Seite 3061-8
1. Verfasser: Gunawan, Rico C (VerfasserIn)
Weitere Verfasser: Choban, Eric R, Conour, John E, Silvestre, Jonathan, Schook, Lawrence B, Gaskins, H Rex, Leckband, Deborah E, Kenis, Paul J A
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Biomarkers Collagen Type I Laminin Proliferating Cell Nuclear Antigen