Analysis of children with type 1 diabetes in Korea high prevalence of specific anti-islet autoantibodies, immunogenetic similarities to Western populations with "unique" haplotypes, and lack of discrimination by aspartic acid at position 57 of DQB

Analysis of children with type 1 diabetes in Korea : high prevalence of specific anti-islet autoantibodies, immunogenetic similarities to Western populations with "unique" haplotypes, and lack of discrimination by aspartic acid at position 57 of DQB

This study analyzed the expression of anti-islet autoantibodies and HLA-DR and -DQ genotypes in Korean children with type 1 diabetes mellitus (T1DM). The positivity of the anti-ICA512, anti-GAD65, and anti-insulin autoantibodies in the newly onset T1DM patients (n = 15) was 66.7%, 86.7%, and 46.7%,...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 113(2004), 3 vom: 12. Dez., Seite 318-25
Auteur principal: Yu, Jeesuk (Auteur)
Autres auteurs: Shin, Chung Ho, Yang, Sei Won, Park, Myoung Hee, Eisenbarth, George S
Format: Article
Langue:English
Publié: 2004
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Comparative Study Journal Article Research Support, Non-U.S. Gov't Autoantibodies HLA-DQ Antigens HLA-DQ beta-Chains HLA-DQB1 antigen HLA-DR Antigens HLA-DRB1 Chains HLA-DRB1*03:01 antigen plus... Aspartic Acid 30KYC7MIAI