A perforin/granzyme-positive MDS-derived T cell line, K2-MDS, induces apoptosis in CD34+ cells through the fractalkine-CX3CR1 system

Fractalkine (CX3CL1) and its receptor CX3CR1 play an important role in natural killer (NK) cell- and cytotoxic T cell-mediated endothelium damage. Here we describe the cytotoxicity of myelodysplastic syndrome (MDS)-derived T cell line, K2-MDS, through the fractalkine-CX3CR1 system. K2-MDS cells indu...

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Publié dans:	Clinical immunology (Orlando, Fla.). - 1999. - 113(2004), 1 vom: 15. Okt., Seite 109-16
Auteur principal:	Morita, Yasuyoshi (Auteur)
Autres auteurs:	Matsuda, Mitsuhiro, Hanamoto, Hitoshi, Shimada, Takahiro, Tatsumi, Yoichi, Maeda, Yasuhiro, Kanamaru, Akihisa
Format:	Article
Langue:	English
Publié:	2004
Accès à la collection:	Clinical immunology (Orlando, Fla.)
Sujets:	Journal Article Research Support, Non-U.S. Gov't Antigens, CD34 CX3C Chemokine Receptor 1 CX3CL1 protein, human CX3CR1 protein, human Chemokine CX3CL1 Chemokines, CX3C Membrane Proteins Receptors, Chemokine