Hemagglutinating virus of Japan protein is efficient for induction of CD4+ T-cell response by a hepatitis B core particle-based HIV vaccine

Hemagglutinating virus of Japan protein is efficient for induction of CD4+ T-cell response by a hepatitis B core particle-based HIV vaccine

By using the hepatitis B core (HBc) protein gene as a carrier, HIV-1 env V3 gene was inserted into the carrier gene, and the HIV gene was expressed inside a chimeric HIV-HBc particle (HIV-HBc), which was a unique candidate for induction of HIV-specific CTL activity. This was seen significantly in mi...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 112(2004), 1 vom: 16. Juli, Seite 92-105
1. Verfasser: Takeda, Satoshi (VerfasserIn)
Weitere Verfasser: Shiosaki, Kouichi, Kaneda, Yasufumi, Nakasatomi, Tetsuya, Yoshizaki, Hitomi, Someya, Kenji, Konno, Yusuke, Eda, Yasuyuki, Kino, Youichirou, Yamamoto, Naoki, Honda, Mitsuo
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't AIDS Vaccines HIV Antibodies HIV Envelope Protein gp120 Hepatitis B Core Antigens Interleukins Liposomes Recombinant Fusion Proteins Interferon-gamma 82115-62-6