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01000caa a22002652 4500 |
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NLM147651174 |
| 003 |
DE-627 |
| 005 |
20250205115129.0 |
| 007 |
tu |
| 008 |
231223s2004 xx ||||| 00| ||chi c |
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5 |
2 |
|a pubmed25n0492.xml
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| 035 |
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|a (DE-627)NLM147651174
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| 035 |
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|a (NLM)15068714
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| 040 |
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Hu, Dian-lei
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Clinical significance of serum S-100B protein in severe cerebral injury
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| 264 |
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1 |
|c 2004
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 07.10.2004
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| 500 |
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|a Date Revised 21.11.2013
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| 500 |
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a OBJECTIVE: To investigate the value of S-100B protein as a biology marker in diagnosis and prognostic after severe cerebral injury
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| 520 |
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|a METHODS: Sixty-six patients with severe head injury (Glasgow coma scale score (GCS)<or=8) were included in this study, venous blood samples for S-100B protein were obtained as soon as possible after admission and every 24 hours thereafter for a maximum of 3-7 consecutive days. Serum levels of S-100B protein were compared with outcome (Glasgow outcome scale score, GOS) after 6 months
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| 520 |
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|a RESULTS: Of 66 patients, 25 patients died, mutilation in 22 patients, 19 patients had a good outcome. Patients who died had significantly higher serum S-100B values compared with those who survived (median 2.60 microg/L vs. 0.55 microg/L, P<0.001), 14 of 25 patients who died had peak S-100B values of 2.00 microg/L or higher, compared with 4 of 41 surviving patients (P<0.005)
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| 520 |
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|a CONCLUSION: S-100B protein has a reliable value in diagnosis and prognostic after severe head injury
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| 650 |
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4 |
|a English Abstract
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| 650 |
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4 |
|a Journal Article
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| 650 |
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4 |
|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Nerve Growth Factors
|2 NLM
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| 650 |
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7 |
|a S100 Calcium Binding Protein beta Subunit
|2 NLM
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| 650 |
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7 |
|a S100 Proteins
|2 NLM
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| 700 |
1 |
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|a Liu, Xian-hua
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yu, Xiao-liang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Guo, Hong-mei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Guo, Bing
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Shi, Yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhuang, Hui-lin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Shi, Peng
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 16(2004), 4 vom: 06. Apr., Seite 221-2
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
1 |
8 |
|g volume:16
|g year:2004
|g number:4
|g day:06
|g month:04
|g pages:221-2
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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| 912 |
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|a GBV_ILN_350
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| 951 |
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|a AR
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| 952 |
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|d 16
|j 2004
|e 4
|b 06
|c 04
|h 221-2
|