In vitro and in vivo T cell oligoclonality following chronic stimulation with staphylococcal superantigens
Microbial superantigens (SAg), including SEB and TSST-1, polyclonally activate T cells belonging to specific TCR BV families. A pathogenic role for SAg in various human diseases has been suggested, but enthusiasm for this view has been tempered by the T cell oligoclonality in these disorders. To ass...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 3 vom: 19. Sept., Seite 182-9 |
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| Format: | Aufsatz |
| Sprache: | English |
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2003
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Bacterial Toxins Complementarity Determining Regions Enterotoxins HLA-DQ Antigens HLA-DQ8 antigen HLA-DR2 Antigen Superantigens mehr... |