The tandem-repeat polymorphism of the DC-SIGNR gene does not affect the susceptibility to HIV infection and the progression to AIDS

The tandem-repeat polymorphism of the DC-SIGNR gene does not affect the susceptibility to HIV infection and the progression to AIDS

DC-SIGNR is a C-type lectin that functions as a transreceptor for HIV-1. The exon 4 of the DC-SIGNR gene comprises a variable number of 69-bp tandem repeats, encoding for parts of the extracellular protein domain. Here, we analyzed the relevance of this gene polymorphism for the interindividual tran...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 107(2003), 1 vom: 01. Apr., Seite 55-9
Auteur principal: Lichterfeld, Mathias (Auteur)
Autres auteurs: Nischalke, Hans Dieter, van Lunzen, Jan, Söhne, Jennifer, Schmeisser, Norbert, Woitas, Rainer, Sauerbruch, Tilman, Rockstroh, Jürgen K, Spengler, Ulrich
Format: Article
Langue:English
Publié: 2003
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't CLEC4M protein, human Cell Adhesion Molecules DNA, Viral Lectins, C-Type Receptors, Cell Surface