Selection of scFv phages on intact cells under low pH conditions leads to a significant loss of insert-free phages

Display of functional antibody fragments on the surface of filamentous bacteriophages allows fast selection of specific phage antibodies against a variety of target antigens. However, enrichment of single chain variable fragment (scFv)-displaying phages is often hampered by the abundance of bacterio...

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Détails bibliographiques
Publié dans:BioTechniques. - 1991. - 30(2001), 2 vom: 09. Feb., Seite 404-8, 410, 412-3
Auteur principal: Tur, M K (Auteur)
Autres auteurs: Huhn, M, Sasse, S, Engert, A, Barth, S
Format: Article
Langue:English
Publié: 2001
Accès à la collection:BioTechniques
Sujets:Journal Article Research Support, Non-U.S. Gov't Immunoglobulin Fragments Peptide Library immunoglobulin Fv